Do genetic polymorphisms in angiotensin converting enzyme 2 (ACE2) gene play a role in coronavirus disease 2019 (COVID-19)?
Synthetic α‐Helical Peptides as Potential Inhibitors of the ACE2 SARS‐CoV‐2 Interaction - Engelhardt - 2022 - ChemBioChem - Wiley Online Library
SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein -ACE2 Complex and Antibody Evasion | bioRxiv
ACE2 binding causes dissociation of trimeric SARS-CoV-2 spike, may be used to inhibit further infection
SARS‐CoV‐2 first contact: Spike–ACE2 interactions in COVID‐19 - Nesci - 2021 - Chemical Biology & Drug Design - Wiley Online Library
Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor | Nature Communications
IJMS | Free Full-Text | Geraniin Inhibits the Entry of SARS-CoV-2 by Blocking the Interaction between Spike Protein RBD and Human ACE2 Receptor
Frontiers | The Impact of ACE2 Polymorphisms on COVID-19 Disease: Susceptibility, Severity, and Therapy
SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets | eLife
SARS-CoV-2 and the spike protein in endotheliopathy: Trends in Microbiology
Cell entry mechanisms of SARS-CoV-2 | PNAS
Advances in developing ACE2 derivatives against SARS-CoV-2 - The Lancet Microbe
Frontiers | Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-19
Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains - ScienceDirect
Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain | PLOS ONE
Outsmarting SARS-CoV-2 by empowering a decoy ACE2 | Signal Transduction and Targeted Therapy
Scientists uncover the structural mechanism of coronavirus receptor binding | Crick
Hidden States of the COVID-19 Spike Protein
IJMS | Free Full-Text | Structural and Computational Studies of the SARS-CoV-2 Spike Protein Binding Mechanisms with Nanobodies: From Structure and Dynamics to Avidity-Driven Nanobody Engineering
SARS-CoV-2 Spike-ACE2 Inhibitor Screening Service | Reaction Biology
Engaging the spikes: heparan sulfate facilitates SARS-CoV-2 spike protein binding to ACE2 and potentiates viral infection | Signal Transduction and Targeted Therapy
Computational biophysical characterization of the SARS-CoV-2 spike protein binding with the ACE2 receptor and implications for infectivity - Computational and Structural Biotechnology Journal
Manipulation of ACE2 expression in COVID-19 | Open Heart
An Update on Novel Soluble ACE2 Therapeutics to Treat SARS-CoV-2: Insights from a Preclinical Study in: Kidney News Volume 13 Issue 3 (2021)
Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00385A
PDB-101: Molecule of the Month: SARS-CoV-2 Spike
Researchers discover potential therapeutic targets on SARS-CoV-2 Spike protein | Penn State University
Peptide modelling and screening against human ACE2 and spike glycoprotein RBD of SARS-CoV-2 | In Silico Pharmacology
Global conserved RBD fraction of SARS-CoV-2 S-protein with T500S mutation in silico significantly blocks ACE2 and rejects viral spike | Translational Medicine Communications | Full Text
