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NCI10066: a Phase 1/2 study of olaparib in combination with ramucirumab in  previously treated metastatic gastric and gastroesophageal junction  adenocarcinoma | British Journal of Cancer
NCI10066: a Phase 1/2 study of olaparib in combination with ramucirumab in previously treated metastatic gastric and gastroesophageal junction adenocarcinoma | British Journal of Cancer

Patient disposition. Q2W, once every 2 weeks; RP2D, recommended phase 2...  | Download Scientific Diagram
Patient disposition. Q2W, once every 2 weeks; RP2D, recommended phase 2... | Download Scientific Diagram

Clinical Trial: Gallium maltolate (recommended phase 2 dose) for  Glioblastoma (NCT04319276) - YouTube
Clinical Trial: Gallium maltolate (recommended phase 2 dose) for Glioblastoma (NCT04319276) - YouTube

Abbreviations: CR1, first complete remission; RP2D, recommended phase 2...  | Download Scientific Diagram
Abbreviations: CR1, first complete remission; RP2D, recommended phase 2... | Download Scientific Diagram

Design of selected clinical trials of PROTAC degraders. PK:... | Download  Scientific Diagram
Design of selected clinical trials of PROTAC degraders. PK:... | Download Scientific Diagram

Phase I–II clinical trial design: a state-of-the-art paradigm for dose  finding - ScienceDirect
Phase I–II clinical trial design: a state-of-the-art paradigm for dose finding - ScienceDirect

533 An open label Phase IA/IB study for safety, pharmacokinetics (PK), and  efficacy of ONC 392 as a single agent and in combination with Pembrolizumab  in advanced solid tumors | Journal for
533 An open label Phase IA/IB study for safety, pharmacokinetics (PK), and efficacy of ONC 392 as a single agent and in combination with Pembrolizumab in advanced solid tumors | Journal for

Trial profile. DLT = doselimiting toxicity; RP2D = recommended phase 2 dose  | Download Scientific Diagram
Trial profile. DLT = doselimiting toxicity; RP2D = recommended phase 2 dose | Download Scientific Diagram

Immunogenicity and safety of a third dose of CoronaVac, and immune  persistence of a two-dose schedule, in healthy adults: interim results from  two single-centre, double-blind, randomised, placebo-controlled phase 2  clinical trials -
Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials -

Study Design. Abbreviations: BID, twice daily; HGOC, high‐grade ovarian...  | Download Scientific Diagram
Study Design. Abbreviations: BID, twice daily; HGOC, high‐grade ovarian... | Download Scientific Diagram

Optimal biological dose: a systematic review in cancer phase I clinical  trials | BMC Cancer | Full Text
Optimal biological dose: a systematic review in cancer phase I clinical trials | BMC Cancer | Full Text

Resources | Research | Verastem Oncology
Resources | Research | Verastem Oncology

Patient flow diagram. AUC, area under the curve; RP2D, recommended... |  Download Scientific Diagram
Patient flow diagram. AUC, area under the curve; RP2D, recommended... | Download Scientific Diagram

Clinical Development Strategies and Outcomes in First-in-Human Trials of  Monoclonal Antibodies | Journal of Clinical Oncology
Clinical Development Strategies and Outcomes in First-in-Human Trials of Monoclonal Antibodies | Journal of Clinical Oncology

Illustration of the chronic dose-limiting toxicity (DLT) concept. (*)... |  Download Scientific Diagram
Illustration of the chronic dose-limiting toxicity (DLT) concept. (*)... | Download Scientific Diagram

Table 2 from Dose Escalation Methods in Phase I Cancer Clinical Trials |  Semantic Scholar
Table 2 from Dose Escalation Methods in Phase I Cancer Clinical Trials | Semantic Scholar

Study design. BID twice daily, mCRPC metastatic castration-resistant... |  Download Scientific Diagram
Study design. BID twice daily, mCRPC metastatic castration-resistant... | Download Scientific Diagram

Antitumor T cell responses detected in patients with new vaccine strategy  in immune-cold tumors
Antitumor T cell responses detected in patients with new vaccine strategy in immune-cold tumors

Assessing the reporting quality of early phase dose-finding trial  protocols: a methodological review - eClinicalMedicine
Assessing the reporting quality of early phase dose-finding trial protocols: a methodological review - eClinicalMedicine

A single arm phase Ib/II trial of first-line pembrolizumab, trastuzumab and  chemotherapy for advanced HER2-positive gastric cancer | Nature  Communications
A single arm phase Ib/II trial of first-line pembrolizumab, trastuzumab and chemotherapy for advanced HER2-positive gastric cancer | Nature Communications

Sonrotoclax with Dexamethasone for RR Myeloma | Int'l Myeloma Fn
Sonrotoclax with Dexamethasone for RR Myeloma | Int'l Myeloma Fn

Example 2. A DDP segment: a phase I dose-finding study followed by a... |  Download Scientific Diagram
Example 2. A DDP segment: a phase I dose-finding study followed by a... | Download Scientific Diagram

Overview: Innovative Study Designs vs. Traditional FIH | Precision For  Medicine
Overview: Innovative Study Designs vs. Traditional FIH | Precision For Medicine

Determination of Recommended Phase II Dose of Venetoclax (ABT-199) and  Rituximab for Relapsed/Refractory CLL | Research To Practice
Determination of Recommended Phase II Dose of Venetoclax (ABT-199) and Rituximab for Relapsed/Refractory CLL | Research To Practice

Clinical Trials - Cue Biopharma
Clinical Trials - Cue Biopharma

Randomised Phase 1 clinical trials in oncology | British Journal of Cancer
Randomised Phase 1 clinical trials in oncology | British Journal of Cancer

Determination of Recommended Phase II Dose of Venetoclax (ABT-199) and  Rituximab for Relapsed/Refractory CLL | Research To Practice
Determination of Recommended Phase II Dose of Venetoclax (ABT-199) and Rituximab for Relapsed/Refractory CLL | Research To Practice