Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs | Nature Communications
IJMS | Free Full-Text | Advances in Molecular Dynamics Simulations and Enhanced Sampling Methods for the Study of Protein Systems
Molecular Dynamics Simulation and Prediction of Druggable Binding Sites | SpringerLink
Cryptic drug-binding sites discovered in the | EurekAlert!
CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites - ScienceDirect
GitHub - salilab/cryptosite-web: Web server for prediction of cryptic binding sites
Investigating Cryptic Binding Sites by Molecular Dynamics Simulations | Accounts of Chemical Research
Exploring the structural origins of cryptic sites on proteins | PNAS
Viruses | Free Full-Text | Exploring Conformational Landscapes and Cryptic Binding Pockets in Distinct Functional States of the SARS-CoV-2 Omicron BA.1 and BA.2 Trimers: Mutation-Induced Modulation of Protein Dynamics and Network-Guided Prediction
Mechanical Proteins
a), (b) and (c) define the cryptic drug binding regions of H.... | Download Scientific Diagram
Identification of Cryptic Binding Sites Using MixMD with Standard and Accelerated Molecular Dynamics | Journal of Chemical Information and Modeling
Binding site - Wikipedia
Fragment binding induces changes in the allosteric site. (A) Fragment... | Download Scientific Diagram
Identification of Cryptic Binding Sites Using MixMD with Standard and Accelerated Molecular Dynamics | Journal of Chemical Information and Modeling
Frontiers | Discovery of a cryptic pocket in the AI-predicted structure of PPM1D phosphatase explains the binding site and potency of its allosteric inhibitors
Biomolecular & Pharmaceutical Modelling Group
Viruses | Free Full-Text | Exploring Conformational Landscapes and Cryptic Binding Pockets in Distinct Functional States of the SARS-CoV-2 Omicron BA.1 and BA.2 Trimers: Mutation-Induced Modulation of Protein Dynamics and Network-Guided Prediction
Informatics | Free Full-Text | What Features of Ligands Are Relevant to the Opening of Cryptic Pockets in Drug Targets?
GSK716 binds to a novel cryptic binding site. A Cartoon representation... | Download Scientific Diagram
Structure-Based Analysis of Cryptic-Site Opening - ScienceDirect
Predicting the locations of cryptic pockets from single protein structures using the PocketMiner graph neural network | bioRxiv
Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium | Science Advances
BSM00021: Cryptic-site binding mechanism of medium-sized Bcl-xL inhibiting compounds elucidated by McMD-based dynamic docking simulations - BSM-Arc
